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Displaying: 1 - 6 of 6 Results
Inhibiting Microbial Metabolism of Levodopa to Increase Availability in the CNS
Parkinson’s disease (PD) impacts 10 million people globally, with 60,000 Americans newly diagnosed every year. Levodopa remains the gold standard treatment for PD, despite limitations including side effects and peripheral metabolism. Current…
Investigators
- Emily Balskus
Isolating live cells after high-throughput, long-term, time-lapse microscopy
Researchers led by Johan Paulsson have engineered a high-throughput microfluidic device for multigenerational culturing, imaging, and tracking of single-cell lineages. The platform is highly customizable and is compatible with many cell types,…
Investigators
- Johan Paulsson
Diamond tip for NV (nitrogen vacancy) magnetometry
The ability to map magnetic field distributions with high sensitivity and nanoscale resolution is of crucial importance for fundamental studies ranging from material science to biology, as well as for the development of new applications in…
Investigators
- Amir Yacoby
- Xu Zhou
- Rainer Stohr
- Ling Xie
Photostick: Physical isolation of single cells from tissue, for further propagation and single cell sequencing and omics
Photostick enables the physical selection of single cells from large populations in diverse environments. The novel process entails photochemical immobilization of live cells with patterned illumination, followed by removal of unwanted cells with…
Investigators
- Adam Cohen
- Miao-Ping Chien
Microbiome reagents to treat inflammatory bowel disease and restore gut homeostasis
Reactive oxygen species (ROS) and oxidative stress are believed to cause and/or aggravate several diseases, including inflammatory diseases like inflammatory bowel disease (IBD). Antioxidants have the ability to neutralize the damaging effects of…
Investigators
- Wendy Garrett
Innovative microbiome anti-oxidants to repair UV damaged skin and slow aging
Ultraviolet (UV) radiation from the sun drives accumulation of reactive oxygen species (ROS) and inflammation in the skin. UV radiation also depletes skin cells of antioxidant enzymes, including superoxide dismutase (SOD). Increased ROS and…
Investigators
- Wendy Garrett